Here's another one I was looking at a few days ago, I'm not sure how much they have in common, but here it is anyway.

http://helpx.adobe.com/photoshop/kb/optimize-performance-photoshop-cs4-cs5.html

Awesome links guys! Going to put these settings in place.

Nice.. optimized to the max!

Idk if it's in the article, but if you have a PC run a disk cleanup and defrag the hard drive every now and then. Right click the C: drive and hit Properties. Disk Cleanup will be right under the pie chart, and if you hit the Tools tab up top, you can Check for Errors and Defragment the hard drive. I do all three of these every now and then to help my PC run faster overall.

Mac tip: if your running out of memory and can't/don't want to reboot, open terminal (Applications > Utilities > Terminal), type 'purge' (without the quotes) and hit enter.
This releases any inactive memory.

Adhesive Hippo said:Idk if it's in the article, but if you have a PC run a disk cleanup and defrag the hard drive every now and then. Right click the C: drive and hit Properties. Disk Cleanup will be right under the pie chart, and if you hit the Tools tab up top, you can Check for Errors and Defragment the hard drive. I do all three of these every now and then to help my PC run faster overall.

Or download both of these -

http://www.piriform.com/defraggler

http://www.piriform.com/ccleaner

Both are amazing and will keep your system in check.