Do you have any functionality issues when this appears or do you carry on as normal? i often get a similar notification at work as the fonts are stored on a server, but rarely notice any change.

Yeah I haven't found a single issue. Seems fine. Just always pops up when starting up.

Hmm, thats annoying. if youre hosting/storing your fonts on something other than your computers HD I would assume thats the reason. if not, then, thats equally annoying.

Extensis is a company that produces font management software i.e. Extensis Suitcase. If you don't have that installed, it would seem that Photoshop is incorrectly looking for a plugged in application that you don't have. Maybe a reinstall of the Adobe Software? I'm sure other people are having the same issue and have found some sort of fix/workaround.

It looks like you have the Suitcase Fusion auto-activation plug-ins installed and active, but no longer have the application installed. For troubleshooting, I recommend using our knowledge base. This article shows you where all of the plug-ins are installed http://www.extensis.com/support/knowledge-base/troubleshooting-auto-activation-in-suitcase-fusion-3/

You can also contact our support teams at any time.

Jim Kidwell
Extensis